Developed in the 1970s Oxiracetam is a potent member of racetam like piracetam and aniracetam. It is also known as synthetic form of piracetam- the first “smart drug” nootropic.

It is a brain supplement with a slightly different molecular structure from that of piracetam but the almost same mechanism of action like that of the class of racetam supplement.

Considered as a pure nootropic Oxiracetam has a wide range of unique effects. It reduces the cognitive decline which then provides a wide range of cognitive abilities like improved attention span, better concentration, logical thinking.

Users say that they feel more focused and motivated because this stimulant has increased their mental energy.

Not only this, there is a clinical evidence which shows that Oxiracetam can help restore memory. A comparative study was conducted on mice, and the results were that Oxiracetam is even more potent in several areas than piracetam.

Oxiracetam powder is a nootropic which quickly dissolves in the water and is being easily utilized by the body without feeling any agitation which is a very common with other supplements. Unlike those; Oxiracetam is very smooth and mild.

So we can say that Oxiracetam is a very useful nootropic but it needs to be taken in a correct dosage other we may experience some side effects also. You can get all the information on Oxiracetam dosage but first let’s see how it works, its benefits and some other aspects.

How Oxiracetam works

Oxiracetam is one of the most famous and effective brain stimulants; its primary usage is for enhancing cognitive abilities also it has a wide range of benefits such as improvement in memory, focus, thinking capacities, etc. The stimulant is also found to be quite active in increasing your attention, alertness like most other nootropics.

How Oxiracetam Works

Oxiracetam has a similar way of functioning to the other racetam-class supplements, i.e. It stimulates the neurotransmitters to facilitate the release of certain specific brain chemicals. It is known to affect the specific areas in the brain which are responsible for memory, learning, and other important cognitive functions. The glutamate receptor in the brain gets affected by the drug, and the respective neurotransmitter gets activated leading to an improvement in the overall cognitive abilities as well as your ability to focus, learn and remember important things, etc.

The drug Oxiracetam is a central nervous system stimulant and has been found to be quite effective in improving the neuronal communication. This means that the drug also improves the overall nerve-related functions in the body.

Acetylcholine is a compound that is very important for the formation of long-term as well as short-term memory and Oxiracetam stimulates PKC, as well as acetylcholine release.

Oxiracetam Effects

Oxiracetam is a standout amongst the most prominent nootropics, understood and exceptionally respected for its remarkable subjective improvement properties. It offers some benefits which are listed here:-

Enhanced Memory

This benefit is especially beneficial for students who are taking exams or preparing for rational subjects. Not only rational but Oxiracetam is helpful in retaining concepts of calculated and imaginative subjects.

Users of Oxiracetam have noticed that their memory becomes more developed; they can retain and recall things very easily and quickly.

Oxiracetam Benefits

Learning Improvement

Different studies were done on animals, rats, in particular, have shown that oxiracetam makes learning quicker and simpler. This is mainly because of enhanced learning which helps in recalling things quickly.

Sensational Feeling


Because Oxiracetam also increases the functioning of our left part of the brain; some people experiences some sensational feelings like visual observation becoming more colorful and sound, or music becomes deeper.

Oxiracetam Benefits


Oxiracetam is favorite among its user for this benefit. It improves the concentration and focus power of the user, making it easier for them to stick to a particular agenda for a longer period without any distractions. It comes more in use while exam times.

But these are the benefits which one will see only when they are taking Oxiracetam in right dosage otherwise these benefits can even turn into side effects. So let’s understand what the Oxiracetam right dosage is.

Oxiracetam Dosage Schedule

Oxiracetam is a well endured and safe medicine which has been tried for years to test any side effects. But still, it is recommended to have a safe Oxiracetam dosage schedule to avoid any unpleasant effects. Also when it is taken in the recommended range, then its effects on the memory and mood are much better.

Now the dosage schedule can be divided into three parts for the beginners who are using it for the first time, for people who are already using it and for people who plan on increasing its dosage.

If someone is just beginning to use the nootropic drugs, they should begin with a smaller dose of around 750-800 mg per dose twice a day or lower then this is also fine. The main reason behind taking this small amount of dose is to let your body get prepared for this type of drug and avoid any health concerns which may occur by taking heavy doses.

For those who are already using Oxiracetam but don’t know the proper dosage, the range for them is 800-2400 mg per day. This dose can be divided into three parts of 800 mg each. These three intervals can be; one dose after waking up, one after lunch and the last one in the evening 6-7 hours before sleep because Oxiracetam has a half-life of 3-4 hours.

Oxiracetam Dosage

For those who are thinking of increasing of Oxiracetam dosage can do that easily once they have understood how their body reacts to the drug. One can increase the dosage by approx 50mg each time. But there should be a saturation point after which its dosage should not be increased because then it can become harmful.

Now there are two possible strategies for dosing one is using attack dose and the other is using a mega dose.

Attack dose is a high dose taken when you are first starting taking nootropic so that there is a kick start in the effects of the supplement in the body.

The Mega dose is taken by the experienced user; they take approximately two to three times the normal dosage to intensify the effects of the drug.

While some people prefer taking attack dose or mega dose, caution should be taken so as to avoid the unwanted and unpleasant side effects.

Cycling and Stacking Advice

Although Oxiracetam does not have many reports on user experiencing tolerance; but still to be on a safer side, it is recommended to take it in cycles. Cycles can be of two types one is day’s cycle, and one is week cycles. Days cycle means that you take Oxiracetam on one day and the other day is an off and week cycle means that you take Oxiracetam a week and then complete next week is an off.

So when you feel comfortable with both dosage and cycle of Oxiracetam, then you can think of stacking it with other supplements to get the synergetic effect.

Oxiracetam is a member of racetam family, and like them, it also tends to reduce the level of acetylcholine in the brain. And the user feels this reduction in the form of a headache. But not everyone feels this, and for those who feel like this, it is recommended to stack Oxiracetam with choline supplement.

Oxiracetam and Choline supplement

Combining Oxiracetam with choline in daily routine is very beneficial for the long run as it will not only improve the benefits of Oxiracetam but will also reduce the headache which is the most common side effect of Oxiracetam.

Oxiracetam with Pramiracetam

Both belongs to the family of racetam and goes very well together. When combined the dosage becomes very powerful it increases the cognitive abilities of alertness and mental energy to a new level.

Oxiracetam with aniracetam

Same as with pramiracetam, Oxiracetam and Aniracetam work very well together. Their combination helps in reducing anxiety and uplifting the mood which is very beneficial for the user.

Oxiracetam Side Effects

It can be said that Oxiracetam is one of the best nootropic supplement because it is very safe and toxic free. It has been used for years with as such no major complaints about it.

Only one thing which gives the trouble is that it causes mild headaches because it reduces the level of choline in the body and is therefore advised to be used with choline supplement.

And when one is taking Oxiracetam in high dosage and that too for a long period then it might cause some digestion and gastric problems. So the solution is to take recommended dosage and in cycles.

Some users have very rarely experienced nervousness and insomnia and that too because of taking Oxiracetam at the end of the day before sleeping. This can easily be avoided by taking Oxiracetam at the right time.

Oxiracetam Tolerance

Tolerance is a phenomenon, wherein your body stops reacting to the drug or nootropic that you have been taking for a long time since over a period of time your body has become used to the drug’s composition and has adapted itself to it effectively reducing the efficacy of the nootropic being employed.

Mostly, the effects of Oxiracetam lasts for about a month and a half post which the effects begin to reduce gradually. This reduction in the efficacy is because your body has developed tolerance against the drug Oxiracetam. Some studies suggest that trying some stacks of nootropics can help overcome the tolerance developed by the body however the probability of this working is very rare, and there are few success stories in this regard. An ALCAR and choline stack is one of the recommended nootropic stacks for this.

The studies also recommend employing higher doses of the drug Oxiracetam to combat the tolerance and is also found effective in reducing tolerance in about 3 -7 days. Interestingly, Oxiracetam has a cross tolerance effect wherein after taking the drug, other nootropics such as Noopept has a reduced effect.

Another effective to combat tolerance for Nootropics or even specifically for Oxiracetam is by cycling the drug and changing your dosage as well as altering the timings of consumption for the drug.

Oxiracetam Half-Life

Orixacetam as a brain stimulant is absorbed in the intestines after reaching levels in the blood stream within one to three hours post consumption after a single 800-2000mg dosage. The half-life or the time taken by the drug Orixacetam to reduce to half of its pharmacologic or radioactive activity is about 8 hours if you do not have any other pre-existing conditions. In case of presence of any renal issues, the half-life for Oxiracetam is 10-68 hours.

The half-life of a drug has a huge effect on deciding the ideal dosage for Oxiracetam and proves that taking high dosages will only put strain on the body but not have any drastic effects on cognitive enhancement or other related benefits of the drug. The most important conclusion that we can derive from the relationship of dosage and half-life in Oxiracetam is that you can take smaller dosages as the drug is found to be potent when compared to other nootropic. However, it is recommended to take the drug twice a day for better results.

On the other hand, some studies have found that the terminal half-life for Oxiracetam is 3-4 hours hence the recommended dosage of 600-2000mg per day should be broken into several small dosages throughout the day so that the effect of the drug lasts and the efficiency is not reduced.


Oxiracetam racetam is a standout amongst the most nootropics, considered by numerous clients to be an unquestionable supplement which can work great alone also and can also mix with different supplements. Oxiracetam works as a focal sensory stimulant which builds mental and physical readiness without any anxiety or restlessness. It's a great decision for students, specialists, scholars, or anybody else who need sustained mental vitality for broadened timeframes.